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League Table : 2021
| Pos | Team | Live | Pld | W | D | L | +/- | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Colo-Colo | 25 | 16 | 4 | 5 | 22 | 52 | WLWWW | |
| 2 |  Universidad Católica | 25 | 16 | 2 | 7 | 18 | 50 | WWWWW | |
| 3 |  Audax Italiano | 26 | 12 | 8 | 6 | 5 | 44 | WWLWL | |
| 4 |  Unión La Calera | 1-2 | 25 | 13 | 5 | 7 | 4 | 44 | WWWLW |
| 5 |  Unión Española | 26 | 13 | 3 | 10 | 5 | 42 | LWLWW | |
| 6 |  Everton Viña del Mar | 25 | 10 | 7 | 8 | 1 | 37 | DWWLW | |
| 7 |  Cobresal | 1-2 | 26 | 10 | 5 | 11 | 3 | 35 | WLLLL |
| 8 |  Deportes Antofagasta | 25 | 9 | 8 | 8 | -1 | 35 | LDWWL | |
| 9 |  Universidad de Chile | 25 | 9 | 7 | 9 | 2 | 34 | LDLLL | |
| 10 |  Ñublense | 26 | 8 | 9 | 9 | 4 | 33 | WLDLW | |
| 11 |  Palestino | 25 | 9 | 5 | 11 | -1 | 32 | DLWDW | |
| 12 |  Deportes La Serena | 26 | 8 | 8 | 10 | -1 | 32 | LWWDL | |
| 13 |  O'Higgins | 26 | 7 | 8 | 11 | -11 | 29 | WLWDL | |
| 14 |  Curicó Unido | 25 | 6 | 9 | 10 | -4 | 27 | DWWDL | |
| 15 |  Deportes Melipilla | 26 | 6 | 8 | 12 | -15 | 26 | LDLDW | |
| 16 |  Huachipato | 25 | 4 | 11 | 10 | -10 | 23 | LLLLL | |
| 17 |  Santiago Wanderers | 25 | 5 | 3 | 17 | -21 | 18 | WDLWL |
